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CAS RN: 113-98-4 | 产品编码: P1772

Penicillin G Potassium Salt


纯度/分析方法: >98.0%(HPLC)(N)
别名:
  • 青霉素G钾盐
  • Benzylpenicillin Potassium Salt
产品文档:
25G
S$100.50
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补充产品信息:

This product has not been tested for potency and is guaranteed for chemical purity.

产品编码 P1772
纯度/分析方法 >98.0%(HPLC)(N)
分子式/分子量 C__1__6H__1__7KN__2O__4S = 372.48 
外观与形状(20°C) 固体
储存温度 室温 (15°C以下阴凉干燥处)
储存在惰性气体下 存放于惰性气体之中
应避免的情况 湿气 (吸湿)
CAS RN 113-98-4
相关CAS RN 61-33-6
Reaxys-RN 3832841
PubChem物质ID 87560525
Merck Index (14) 7094
MDL编号

MFCD00036193

技术规格
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Specific rotation [a]20/D +270.0 to +300.0 deg(C=1, H2O)
物性(参考值)
熔点 217 °C(dec.)
比旋光度 [α]D 294° (C=1,H2O)
水溶性 可溶
GHS
象形图 Pictogram
信号词 Danger
危险性说明 H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
防范说明 P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P272 : Contaminated work clothing should not be allowed out of the workplace.
P280 : Wear protective gloves.
P284 : Wear respiratory protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
相关法规
RTECS# XH9700000
运输信息
HS编码* 2941.10-000
*此H.S.编码用于日本出口报关,不适用于您所在国家或地区的进口申报
应用
Penicillin G: The First Antibiotic belongs to Penicillins

Penicillin is the first antibiotic isolated from the mold Penicillium noctum, specifically it is known as penicillin G (other name: benzylpenicillin) and belongs to a class of similar antibiotics called penicillins. Nowadays penicillin G is produced by Penicillium chrysogenum fermentation. Penicillin G has activity against Gram-positive bacteria, but less activity against Gram-negative bacteria. It acts as a competitive inhibitor of the enzyme transpeptidase, which is needed by bacteria to make their cell walls. Meanwhile, β-lactamases (also called penicillinases) are enzymes produced by bacteria that deactivate penicillin G by destroying the β-lactam ring via hydrolysis. In rare cases, an allergy to penicillin G can cause an anaphylactic reaction, which can be deadly. Currently, the enzymatic hydrolysis of penicillin G gives 6-aminopenicillanic acid (6-APA) [A0800], which is a basic raw material for the industrial production of semisynthetic β-lactamase-resistant and broad spectrum penicillins such as amoxycillin [A2099] and ampicillin [A2092].

References


参考文献


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