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CAS RN: 23288-49-5 | 产品编码: P2002
Probucol
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 125.0 to 128.0 °C |
物性(参考值)
| 熔点 | 128 °C |
| 水溶性 | 不溶 |
| 溶解性(可溶于) | 甲醇, 丙酮, 四氢呋喃 |
GHS
相关法规
| RTECS# | AL3705000 |
运输信息
| HS编码* | 2930.90-900 |
应用
Studies of the Effects of Probucol on Low Density Lipoproteins (LDL)
References
- Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit
- Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemia rabbit, an animal model for familial hypercholesterolemia
- Probucol inhibits oxidative modification of low density lipoprotein
- Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation
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