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CAS RN: 132-20-7 | 产品编码: P2271
Pheniramine Maleate
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 106.0 to 110.0 °C |
物性（参考值）
| 熔点 | 108 °C |
| 最大吸收波长 | 262 nm |
| 溶解性（微溶于） | 苯, 乙醚 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | UT0175000 |
运输信息
| HS编码* | 2933.39-000 |
应用
Pheniramine Maleate: A Histamine H1-Receptor Antagonist
Pheniramine maleate, a first generation antihistamine, is a histamine H1-receptor antagonist. It appears to compete with histamine for histamine H1-receptor sites on effector cells, and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It also has anticholinergic and moderate sedative effects. On the other hand, pheniramine has been reported it as a corrosion inhibitor for mild steel in hydrochloric acid solution.
References
- Histamine antagonists. γ,γ-Disubstituted N,N-dialkyl-propylamines
- Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs
- Simultaneous determination of pseudoephedrine, pheniramine, guaifenesin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography
- Spinal anesthesia with diphenhydramine and pheniramine in rats
- Inhibition of mild steel corrosion in acid solution by Pheniramine drug: Experimental and theoretical study
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