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CAS RN: 544-31-0 | 产品编码: P2670
Palmitoylethanolamide
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| 产品编码 | P2670 |
纯度/分析方法 
|
>98.0%(GC) |
| 分子式/分子量 | C__1__8H__3__7NO__2 = 299.50 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| CAS RN | 544-31-0 |
| PubChem物质ID | 468592667 |
| Merck Index (14) | 6995 |
| MDL编号 | MFCD00020562 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 97.0 to 101.0 °C |
物性（参考值）
| 熔点 | 99 °C |
GHS
相关法规
| RTECS# | ML8950000 |
运输信息
| HS编码* | 2924.19-000 |
应用
Palmitoylethanolamide: A Lipid-Signaling Molecule with Anti-Inflammatory Properties Mediated by PPARα
Palmitoylethanolamide (PEA), an endogenous fatty acid amide, belongs to N-acylethanolamines (NAEs) which are an important family of lipid-signaling molecules such as an endogenous cannabinoid receptor agonist; arachidonylethanolamide (anandamide) (AEA), and a modulator of appetite; oleoylethanolamide (OEA).1,2) Palmitoylethanolamide reportedly has anti-inflammatory properties mediated by peroxisome proliferator-activated receptor-alpha (PPARα).2-4)
References
- 1) N-Acylethanolamines in human reproductive fluids (a review)
- 2) Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors (a review)
- 3) The nuclear receptor peroxisome proliferator-activated receptor-α mediates the anti-inflammatory actions of palmitoylethanolamide
- 4) The search for the palmitoylethanolamide receptor (a review)
- 5) Quantification of Bioactive Acylethanolamides in Rat Plasma by Electrospray Mass Spectrometry
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