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CAS RN: 68-35-9 | 产品编码: S0579
技术规格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 99.0 area% |
Purity(Neutralization titration) | min. 99.0 % |
NMR | confirm to structure |
物性(参考值)
熔点 | 256 °C(dec.) |
水溶性 | 不溶 |
溶解性(可溶于) | 二甲基甲酰胺 |
溶解性(微溶于) | 丙酮 |
溶解性(不溶于) | 乙醚, 乙醇 |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
RTECS# | WP1925000 |
运输信息
HS编码* | 2941.90-000 |
应用
Sulfadiazine, an inhibitor of dihydropteroate synthase
Sulfadiazine is one of the sulfonamides and has an anti-bacterial effect. It inhibits dihydropteroate synthase of bacteria, protozoa and fungi resulting in inhibition of DNA or RNA synthesis of bacteria and other microbes. It also shows anti-toxoplasma effect by using together with pyrimethamine [P2037]. The mammals including human do not have this part of folate synthetic system, so that it is considered to be non-effective for them. (The product is for research purpose only.)
References
- Chemotherapy. II. Some sulfanilamido heterocycles
- Sulfadiazine (a review)
- Toxoplasmosis (a review)
- Dihydrofolate reductase inhibitors as antibacterial agents (a review)
参考文献
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化学品安全说明书(SDS)
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技术规格
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