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CAS RN: 674773-07-0 | 产品编码: S0938
Strontium Ranelate Hydrate
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| 产品编码 | S0938 |
纯度/分析方法 
|
>97.0%(T) |
| 分子式/分子量 | C__1__2H__6N__2O__8SSr__2·xH__2O = 513.49 (as Anhydrous) |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 674773-07-0 |
| 相关CAS RN
|
135459-87-9 |
| Reaxys-RN | 10746913 |
| PubChem物质ID | 253660598 |
| Merck Index (14) | 8106 |
| MDL编号 | MFCD09038742 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Chelometric Titration) | min. 97.0 %(calcd.on anh.substance) |
| NMR | confirm to structure |
物性（参考值）
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
相关法规
| RTECS# | XM7581000 |
运输信息
| HS编码* | 2934.99-000 |
应用
Strontium Ranelate: A Compound with a Dual Mode of Action Optimizing Bone Formation and Resorption
Strontium ranelate (S12911) is composed of an organic moiety (ranelic acid) and of two atoms of stable non-radioactive strontium. In vitro, strontium ranelate increases collagen and noncollagenic proteins synthesis by mature osteoblast enriched cells. Strontium ranelate decreases bone resorption and increases bone formation, resulting in increased bone mass. Therefore, it is called as a “dual action bone agent" (DABA).
References
- An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats
- The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro
- Incorporation and distribution of strontium in bone (a review)
- The biological role of strontium (a review)
- Strontium ranelate: New insights into its dual mode of action (a review)
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