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CAS RN: 481-53-8 | 产品编码: T2708
Tangeretin
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| 产品编码 | T2708 |
| 纯度/分析方法 | >96.0%(HPLC) |
| 分子式/分子量 | C__2__0H__2__0O__7 = 372.37 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片）, 10MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 481-53-8 |
| Reaxys-RN | 351695 |
| PubChem物质ID | 125307389 |
| MDL编号 | MFCD00017438 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Melting point | 153.0 to 157.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 155 °C |
GHS
相关法规
| RTECS# | DJ3102725 |
运输信息
| HS编码* | 2932.99-000 |
应用
Tangeretin: A Polymethoxylated Flavonoid with Anticancer and Antioxidant Activities
Tangeretin, a polymethoxylated flavonoid contained in peels of citrus fruits, is known to have anticancer and antioxidant activities. Recent studies have shown that tangeretin induces cell-cycle G1 arrest, and suppresses cyclooxygenase-2 (COX-2) expression. (The product is for research purpose only.)
References
- Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells
- Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells
- Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass? (a review)
- Tangeretin suppresses IL-1beta-induced cyclooxygenase (COX)-2 expression through inhibition of p38 MAPK, JNK, and AKT activation in human lung carcinoma cells
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