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CAS RN: 440-17-5 | 产品编码: T2849
Trifluoperazine Dihydrochloride
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on dried substance) |
| Drying loss | max. 3.0 % |
物性（参考值）
| 熔点 | 293 °C(dec.) |
| 最大吸收波长 | 312 nm (MeOH) |
| 溶解性（不溶于） | 乙醚, 苯 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | SP1750000 |
运输信息
| HS编码* | 2934.30-000 |
应用
Trifluoperazine Dihydrochloride: A Phenothiazine Dopamine D2 Receptor Antagonist
Trifluoperazine dihydrochloride is a phenothiazine dopamine receptor antagonist which has been extensively used for its antipsychotic properties. However, recently, there is good evidence to suggest that, in common with other phenothiazine agents, trifluoperazine has important antibacterial activity. (The product is for research purpose only.)
References
- Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
- Antipsychotic drug doses and neuroleptic/dopamine receptors
- Changes in dopamine-mediated behavior during one year's neuroleptic administration
- The broad-spectrum antimycobacterial activities of phenothiazines, in vitro: somewhere in all of this there may be patentable potentials (a review)
- Trifluoperazine hydrochloride (a review on the description, physical properties, synthesis, identification, stability, metabolism, and analysis)
- Derivative spectrophotometric, thin layer chromatographic-densitometric and high performance liquid chromatographic determination of trifluoperazine hydrochloride in presence of its hydrogen peroxide induced-degradation product
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