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CAS RN: 38748-32-2 | 产品编码: T2899
产品编码 | T2899 |
纯度/分析方法 ![]() |
>98.0%(HPLC) |
分子式/分子量 | C__2__0H__2__4O__6 = 360.41 |
外观与形状(20°C) | 固体 |
储存温度 ![]() |
冷藏 (0-10°C) |
应避免的情况 | 加热 |
包装和容器 ![]() |
10MG-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 38748-32-2 |
Reaxys-RN | 1692435 |
PubChem物质ID | 172089133 |
Merck Index (14) | 9747 |
MDL编号 | MFCD00210565 |
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Melting point | 228.0 to 235.0 °C |
Specific rotation [a]20/D | -165.0 to -159.0 deg(C=0.15, MeOH) |
物性(参考值)
熔点 | 229 °C |
GHS
象形图 |
![]() |
信号词 | Danger |
危险性说明 | H300 : Fatal if swallowed. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
RTECS# | YK7751000 |
运输信息
UN编号 | UN2811 |
类别 | 6.1 |
包装类别 | I |
HS编码* | 2932.20-000 |
应用
Triptolide: A Diterpene Triepoxide with Potent Immunemodulation, Anti-Inflammatory and Anti-Tumor Properties
Triptolide, a diterpene triepoxide, is a major compornent in the extract of Chinese herb Tripterygium wilfordii Hook F (TWHF). Triptolide reportedly has multiple pharmacological activities including anti-inflammatory, immunemodulation, antiproliferative and pro-apoptotic activity. Triptolide cannot only induce tumor cell apoptosis directly, but can also enhance apoptosis induced by cytotoxic agents by inhibiting NFκB activation. (The product is for research purpose only.)
References
- Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae) (a review)
- Triptolide and its expanding multiple pharmacological functions (a review)
- Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms (a review)
- Triptolide: Progress on research in pharmacodynamics and toxicology (a review)
- Determination of triptolide in root extracts of Tripterygium wilfordii by solid-phase extraction and reverse-phase high-performance liquid chromatography
- Liquid chromatographic/mass spectrometry assay of triptolide in dog plasma and its application to pharmacokinetic study
应用
Studies of the Drug Delivery of Triptolide
References
- Solid lipid nanoparticle and microemulsion for topical delivery of triptolide
- A study of microemulsion systems for transdermal delivery of triptolide
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