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CAS RN: 67-30-1 | 产品编码: T3730
3,3',5,5'-Tetraiodothyroacetic Acid
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| 产品编码 | T3730 |
| 纯度/分析方法 | >98.0%(HPLC)(N) |
| 分子式/分子量 | C__1__4H__8I__4O__4 = 747.83 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片）, 500MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 67-30-1 |
| Reaxys-RN | 2173215 |
| PubChem物质ID | 468592913 |
| MDL编号 | MFCD00055932 |
技术规格
| Appearance | White to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
物性（参考值）
| 熔点 | 230 °C |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H300 : Fatal if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | CY1585800 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | I |
| HS编码* | 2918.99-000 |
应用
3,3',5,5'-Tetraiodothyroacetic Acid: A Thyroid Hormone Analogue with Anti-Angiogenesis and Anti-Tumor Growth Effects
3,3',5,5'-Tetraiodothyroacetic acid is a thyroid hormone (L-thyroxine [T0245]) analogue. It is reported that 3,3',5,5'-tetraiodothyroacetic acid acts at a cell surface receptor to block angiogenic and tumor cell proliferation action of thyroid hormones, which have been recently shown to induce tumor growth and angiogenesis. (The product is for research purpose only.)
References
- Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor
- Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid
- Metabolic Effects of Thyroid Hormone Derivatives (a review)
- Determination of levothyroxine and its degradation products in pharmaceutical tablets by HPLC-UV-ICP-MS
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