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CAS RN: 568-73-0 | 产品编码: T4153
Tanshinone I
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| 产品编码 | T4153 |
纯度/分析方法 
|
>95.0%(HPLC) |
| 分子式/分子量 | C__1__8H__1__2O__3 = 276.29 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 湿气 (吸湿),加热 |
| 包装和容器
|
250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 568-73-0 |
| Reaxys-RN | 237369 |
| MDL编号 | MFCD00210563 |
技术规格
| Appearance | Red to Dark red powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 230.0 to 234.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 231 °C |
GHS
| 危险性说明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相关法规
| RTECS# | SF8282630 |
运输信息
| HS编码* | 2932.99-000 |
应用
Tanshinone I: A Major Lipophilic Component Extracts from the Root of Salvia miltiorrhiza
Tanshinone I, a derivative of phenanthrenequinone, is a major lipophilic component extracted from the root of Salvia miltiorrhiza, which is widely used in Chinese herbal medicine for the treatment of cardiovascular diseases. Biological studies suggested that tanshinone I shows a variety of pharmacological activities, such as anticancer, anti-inflammatory, amyloid-β anti-aggregation and cardio-cerebrovascular protective activities. (The product is for research purpose only.)
Reference
- Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
- Anticancer effects of tanshinone I in human non-small cell lung cancer
- Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses
- S. Y. Kim, T. C. Moon, H. W. Chang, K. H. Son, S. S. Kang, H. P. Kim, Phytother. Res. 2002, 16, 616.
- Research and development of natural product Tanshinone I: pharmacology, total synthesis, and structure modifications (a review)
- Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
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