Maximum quantity allowed is 999
请选择数量
CAS RN: 99300-78-4 | 产品编码: V0110
Venlafaxine Hydrochloride
×
![]()
×
| 产品编码 | V0110 |
纯度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__7H__2__7NO__2·HCl = 313.87 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 应避免的情况 | 光 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 99300-78-4 |
| 相关CAS RN
|
93413-69-5 |
| Reaxys-RN | 4240401 |
| PubChem物质ID | 125307750 |
| SDBS (AIST Spectral DB) | 52922 |
| Merck Index (14) | 9946 |
| MDL编号 | MFCD03658865 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
物性（参考值）
| 熔点 | 217 °C |
| 溶解性（可溶于） | 甲醇 |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H302 : Harmful if swallowed. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | QV8872760 |
运输信息
| HS编码* | 2922.50-000 |
应用
Venlafaxine Hydrochloride: A Serotonin/Norepinephrine Reuptake Inhibitor (SNRI)
Venlafaxine hydrochloride belongs to a serotonin [S0370] /norepinephrine [A0906] reuptake inhibitors (SNRIs). Studies have shown that venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV) [D5598], are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak inhibitors of dopamine [A0305] reuptake. Venlafaxine and ODV have no significant affinity for muscarinic cholinergic, H1-histaminergic, or α1-adrenergic receptors in vitro. For your reference, duloxetine hydrochloride [D4223] and milnacipran hydrochloride [M2133] also belong to SNRIs. (The product is for research purpose only.)
References
- Biochemical, neurophysiological, and behavioral effects of Wy-45,233 and other identified metabolites of the antidepressant venlafaxine
- Venlafaxine oxidation in vitro is catalyzed by CYP2D6
- Venlafaxine: a review of its pharmacology and therapeutic potential in depression (a review)
- Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors
- Use of vancomycin silica stationary phase in packed capillary electrochromatography. II. Enantiomer separation of venlafaxine and O-desmethylvenlafaxine in human plasma
- Development and validation of stability indicating method for the quantitative determination of venlafaxine hydrochloride in extended release formulation using high performance liquid chromatography
参考文献
技术文章
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。