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CAS RN: 60-70-8 | 产品编码: V0148
Veratramine
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| 产品编码 | V0148 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__2__7H__3__9NO__2 = 409.61 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
10MG-Glass Bottle with Plastic Insert （查看图片）, 50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 60-70-8 |
| Reaxys-RN | 55515 |
| PubChem物质ID | 354335607 |
| Merck Index (14) | 9952 |
| MDL编号 | MFCD00468124 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 208.0 to 212.0 °C |
| Specific rotation [a]20/D | -64.0 to -68.0 deg(C=0.5, CHCL3) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 210 °C |
| 比旋光度 [α]D | -66° (C=0.5,CHCl3) |
| 最大吸收波长 | 268 nm |
| 水溶性 | 微溶 |
| 溶解性（可溶于） | 醇, 甲醇, 苯, 氯仿 |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | YX5094000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2939.79-000 |
应用
Veratramine: A Steroidal Alkaloid with Some Bioactivities
Veratramine is a major lipid-soluble steroidal alkaloid existing in Veratrum nigrum L., belongs to the family liliaceae, which is a traditional medicinal plant in China. Veratramine has been reported to teratogenic, anti-tumor and anti-hypertension effects. (The product is for research purpose only.)
References
- The teratogenic Veratrum alkaloid cyclopamine inhibits Sonic hedgehog signal transduction
- Steroidal alkaloids from the roots and rhizomes of Veratrum nigrum L.
- Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrum L. in spontaneously hypertensive rats
- Antitumor and antiplatelet activity of alkaloids from Veratrum dahuricum
- The Veratrum and Solanum alkaloids (a review)
- Metabolism study of veratramine associated with neurotoxicity by using HPLC-MSn
- Identification and characterization of in vitro and in vivo metabolites of steroidal alkaloid veratramine
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