用于近红外(NIR)染料开发的苯并双噻二唑砌块

4,8-二溴苯并[1,2-c:4,5-c']双[[1,2,5]噻二唑] (1)是一种受体结构单元，因其强吸电子特性和原型醌式结构⁶⁾，在功能性染料^1-3)和π共轭高分子^4,5)的开发中具有重要价值。该化合物具有长波长吸收和发光特性，尤其适用于近红外二区 (NIR-II)的染料开发。此类染料可有效减少生物组织散射和自体荧光的干扰，在荧光成像¹⁾，光热治疗 (PTT)²⁾及声动力治疗 (SDT)³⁾领域展现出应用潜力。此外，1还可以用于π共轭高分子材料包括高迁移率有机薄膜晶体管  (OTFT)材料⁴⁾和热电材料⁵⁾的开发。

关键词

D4086

4,8-二溴苯并[1,2-c:4,5-c']双[[1,2,5]噻二唑]

D3842

4,7-二溴-2,1,3-苯并噻二唑

D4734

4,7-二溴-5,6-二氟-2,1,3-苯并噻二唑

文献

• 1) Traumatic Brain Injury Imaging in the Second Near-Infrared Window with a Molecular Fluorophore
  • X.-D. Zhang, H. Wang, A. L. Antaris, L. Li, S. Diao, R. Ma, A. Nguyen, G. Hong, Z. Ma, J. Wang, S. Zhu, J. M. Castellano, T. Wyss-Coray, Y. Liang, J. Luo, H. Dai, Adv. Mater. 2016, 28, 6872.
• 2) Photothermal Therapy of Tuberculosis Using Targeting Pre-Activated Macrophage Membrane-Coated Nanoparticles
  • B. Li, W. Wang, L. Zhao, Y. Wu, X. Li, D. Yan, Q. Gao, Y. Yan, J. Zhang, Y. Feng, J. Zheng, B. Shu, J. Wang, H. Wang, L. He, Y. Zhang, M. Pan, D. Wang, B. Z. Tang, Y. Liao, Nat. Nanotechnol. 2024, 19, 834.
• 3) Autophagy-Enhanced Nanosonosensitizer Mediated Sonodynamic Therapy for Post-Myocardial Infarction Neuromodulation and Arrhythmia Prevention
  • H. Hu, S. Wang, Q. Li, J. Zhao, Y. Pang, J. Wang, H. Wu, X. Wang, Y. Cheng, M. Yu, X. Yin, Y. Zhang, L. Yu, Y. Sun, H. Jiang, Theranostics 2025, 15, 2201.
• 4) High-Performance Ambipolar Transistors and Inverters from an Ultralow Bandgap Polymer
  • J. Fan, J. D. Yuen, M. Wang, J. Seifter, J.-H. Seo, A. R. Mohebbi, D. Zakhidov, A. Heeger, F. Wudl, Adv. Mater. 2012, 24, 2186.
• 5) Thermoelectric Performance in Triplet-Ground-State Polymer Intrinsically Boosted by Enhanced Proquinoidal Characteristic
  • R. Wu, Y. Wei, X. Dai, L. Yan, W. Liu, D. Yuan, J. Zhu, X. Zhu, Angew. Chem. Int. Ed. 2025, 64, e202413061.
• 6) Quinoidal Conjugated Polymers with Open-Shell Character
  • X. Ji, L. Fang, Polym. Chem. 2021, 12, 1347.

返回页首