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Chemiluminescence Reagent for the Detection of Intramitochondrial Superoxide

 MMT (B4339) is a specific probe having lucigenin- like chemiluminescence to superoxide among reactive oxygen species. Since amphiphilic MMT which is less hydrophilic than lucigenin possesses cell-permeability, MMT has been applicable for the detection of intramitochondrial superoxide production.

Application

 Figure shows the localization of MMT in mitochondria.

Figure. Fluorescence in mitochondria in mouse peritoneal neutrophils.
(Provided by Prof. Kobayashi)

 

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