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CAS RN: 912-60-7 | Product Number: N0963

Noscapine Hydrochloride Hydrate


Purity: >98.0%(T)(HPLC)
Synonyms:
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Product Number N0963
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__2H__2__3NO__7·HCl·xH__2O = 449.88  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Hygroscopic,Heat Sensitive
CAS RN 912-60-7
Related CAS RN 128-62-1&219533-73-0
PubChem Substance ID 253660822
MDL Number

MFCD00149223

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D +43.0 to +47.0 deg(C=0.5, 0.1mol/L HCl)(calcd.on anh.substance)
Water 2.0 to 6.0 %
Properties (reference)
Melting Point 200 °C(dec.)
Specific Rotation 45° (C=0.5,0.1 mol/L HCl)
Solubility in water Completely soluble
Solubility (soluble in) Ethanol
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
EC Number 213-014-9
RTECS# NP7225000
Transport Information:
HS Number 2939190000
Application
抗腫瘍性イソキノリンアルカロイド,ノスカピン塩酸塩

Noscapine hydrochloride is an isoquinoline alkaloid found in opium latex, not having anesthetic and analgesic properties. Noscapine is being used as an antitussive agent for a long time has been recently discovered as a novel tubulin-binding, anti-angiogenic anticancer agent that causes cell cycle arrest and induces apoptosis in cancer cells. (The product is for research purpose only.)

References


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