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CAS RN: 54965-24-1 | Product Number: T2510

Tamoxifen Citrate


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (Z)-1-(4-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene Citrate
Documents:
1G
€107.00
4   ≥20 
5G
€370.00
4   ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number T2510
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__6H__2__9NO·C__6H__8O__7 = 563.65  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Hygroscopic,Heat Sensitive
CAS RN 54965-24-1
Related CAS RN 10540-29-1
Reaxys Registry Number 8888650
PubChem Substance ID 87560062
Merck Index (14) 9048
MDL Number

MFCD00058321

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 142 °C(dec.)
Solubility in water Slightly soluble
Solubility (soluble in) Acetone,Ethanol,Methanol
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H360 : May damage fertility or the unborn child.
H362 : May cause harm to breast-fed children.
H350 : May cause cancer.
Precautionary Statements P263 : Avoid contact during pregnancy and while nursing.
P260 : Do not breathe dust or mist.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
Related Laws:
EC Number 259-415-2
RTECS# KH2387000
Transport Information:
HS Number 2921490090
Application
Tamoxifen Citrate: Selective Estrogen Receptor Modulator (SERM)

Tamoxifen citrate is a widely used nonsteroidal anti-estrogen agent for the treatment of hormone-dependent breast cancer. Tamoxifen is a prodrug and extensively metabolized by cytochrome P450 (CYP450) enzymes into active metabolites including 4-hydroxytamoxifen and endoxifen (4-hydroxy-N-desmethyltamoxifen). They act as an estrogen receptor antagonist in breast tissue. Tamoxifen is commonly referred to as a selective estrogen receptor modulator (SERM), since it behaves as an estrogen receptor agonist in other tissues. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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