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CAS RN: 4023-02-3 | Product Number: A2055

1-Amidinopyrazole Hydrochloride

Purity: >98.0%(T)(HPLC)
  • Praxadine
  • 1-Pyrazolecarboxamidine Hydrochloride
  • Pyrazole-1-carboximidamide Hydrochloride
  • 1-Carbamimidoylpyrazole Hydrochloride
≥20  Contact Us
≥20  ≥20 

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.

Product Number A2055
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__4H__6N__4·HCl = 146.58  
Physical State (20 deg.C) Solid
CAS RN 4023-02-3
Reaxys Registry Number 5448758
PubChem Substance ID 87559963
MDL Number


Appearance White to Yellow to Orange powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 165.0 to 169.0 °C
Properties (reference)
Melting Point 167 °C
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
Transport Information:
H.S.code* 2933.19-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.

Typical Procedure:
1-Amidinopyrazole hydrochloride (1 g, 6.8 mmol) is added to a solution of 2-(benzoxazol-2-yl)ethylamine (1.1 g, 6.7 mmol) and diisopropylethylamine (4.75 mL, 27 mmol) in DMF (10 mL). The reaction mixture is stirred at room temperature under N2 for 24 h. Subsequently, diethylether (75 mL) is added, the upper layer is decanted and the remaining oil solidified by treatment with CH2Cl2. The solid is collected, washed with diethylether, CH2Cl2, and CHCl3 : i-PrOH (4 : 1) and dried to yield the product (0.86 g, Y. 52.6%).


PubMed Literature

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