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CAS RN: 98753-19-6 | Product Number: C3007

Cefpirome Sulfate


Purity: >95.0%(HPLC)(N)
Synonyms:
Documents:
1G
$51.00
5   2  
5G
$177.00
1   ≥20 

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Product Number C3007
Purity / Analysis Method >95.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__2__2H__2__2N__6O__5S__2·H__2SO__4 = 612.65  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic,Heat Sensitive
CAS RN 98753-19-6
Related CAS RN 84957-29-9
Reaxys Registry Number 11738005
PubChem Substance ID 253661002
Merck Index (14) 1940
MDL Number

MFCD11864966

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 95.0 area%
Purity(with Total Nitrogen) min. 95.0 %
Specific rotation [a]20/D -27.0 to -33.0 deg(C=2.5,a solution prepared by addition of water to 25mL of actonitrile to make 50mL)(calcd.on anh.substance)
Water max. 5.0 %
Properties (reference)
Melting Point 200 °C
Specific Rotation -30° (C=2.5,JP Method)
Maximum Absorption Wavelength 265(Buffer) nm
Solubility in water Soluble
Solubility (insoluble in) Ether,Ethanol
GHS
Related Laws:
RTECS# UW8970000
Transport Information:
H.S.code* 2941.90-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Cefpirome: A Fourth Generation Cephalosporin with Broad Spectrum of Activity and Stability to β-Lactamases

Cefpirome sulfate is a fourth generation semi-synthetic cephalosporin. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, and is generally more active against Gram-negative bacteria than the first and second generation cephalosporins. While the mechanism of action similar to other cephalosporins (inhibition of peptidoglycan synthesis by cell walls), cefpirome has also activity against Gram-positive coccus (eg. Streptococcus pneumoniae) more than the third generation cephalosporins, regardless of penicillin susceptibility. And it has increased stability to β-lactamases compared with the first and second generation cephalosporins.

References


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