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CAS RN: 71145-03-4 | Product Number: D6040
Bay K 8644
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Purity: >95.0%(HPLC)
Synonyms:
- Methyl 2,6-Dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 20MG |
$264.00
|
30 | 0 | Contact Us |
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| Product Number | D6040 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__5F__3N__2O__4 = 356.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 71145-03-4 |
| Reaxys Registry Number | 453490 |
| MDL Number | MFCD00036697 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 165.0 to 169.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 167 °C |
GHS
Related Laws:
| RTECS# | US5655000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
(±)-Bay K 8644: A Dihydropyridine Calcium Channel Agonist
(±)-Bay K 8644, a structural analog of nifedipine [N0528] (a calcium channel antagonist), is a dihydropyridine calcium channel agonist. It is a racemic mixture composed of two optical isomers, (4R)-(+) and (4S)-(-) forms. (±)-Bay K 8644 has similar effects as its (4S)-(-) form, which activates voltage-sensitive L-type calcium channels. (The product is for research purpose only.)
References
- Dihydropyridine derivatives prolong the open state of calcium channels in cultured cardiac cells
- Kinetic modulation of guinea-pig cardiac L-type calcium channels by fendiline and reversal of the effects of Bay K 8644
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