Maximum quantity allowed is 999
Please select the quantity
CAS RN: 185739-14-4 | Product Number: D6545
2,2-Difluoroethenyl 4-Methylbenzene-1-sulfonate
×
Purity: >98.0%(GC)
Synonyms:
- 2,2-Difluorovinyl 4-Methylbenzenesulfonate
- 2,2-Difluorovinyl Tosylate
- Toluene-4-sulfonic Acid 2,2-Difluorovinyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$83.00
|
16 | 0 | Contact Us | |
| 5G |
$264.00
|
21 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | D6545 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__9H__8F__2O__3S = 234.22 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 185739-14-4 |
| Reaxys Registry Number | 7638656 |
| MDL Number | MFCD27946567 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Flash point | 115 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2905.59-000 |
Application
TCI Practical Example: Suzuki-Miyaura Cross-Coupling of Aromatic Boronic Acids Using a Novel Difluorovinylating Agent
Used Chemicals
Procedure
4-Biphenylboronic acid (100 mg, 0.51 mmol), 2,2-difluorovinyl tosylate (177 mg, 0.76 mmol), Pd2(dba)3 (11.5 mg, 0.01 mmol), and PCy3·HBF4 (9.2 mg, 0.03 mmol) were added into the reaction vessel. To this, tripotassium phosphate (182 mg, 0.86 mmol) in water (670 µL) and THF (3.4 mL) were added subsequentially. The vessel was purged with nitrogen and the mixture was stirred at 70 °C for 20 hours. Then the reaction mixture was filtered under vacuum to remove the insoluble, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane) to afford 4-(2,2-difluorovinyl)biphenyl (93.8 mg, 88% yield) as a white solid.
Experimenter’s Comments
The reaction was monitored by TLC (hexane, Rf = 0.4) and UPLC-MS.
Analytical Data
4-(2,2-Difluorovinyl)biphenyl
1H NMR (400 MHz, CDCl3); δ 7.61- 7.57 (m, 4H), 7.46- 7.33 (m, 5H), 5.32 (dd, J = 26.4, 3.6 Hz, 1H).
Lead Reference
- Direct Vinylation and Difluorovinylation of Arylboronic Acids Using Vinyl- and 2,2-Difluorovinyl Tosylates via the Suzuki-Miyaura Cross Coupling
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.