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CAS RN: 219861-08-2 | Product Number: E0958
(S)-Citalopram Oxalate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Oxalate
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 200MG |
$84.00
|
20 | 6 |
| 1G |
$288.00
|
≥40 | 1 |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | E0958 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__1FN__2O·C__2H__2O__4 = 414.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | 0-10°C |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 219861-08-2 |
| Related CAS RN | 128196-01-0 |
| Reaxys Registry Number | 9826317 |
| PubChem Substance ID | 253660029 |
| Merck Index (14) | 2318 |
| MDL Number | MFCD06407826 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +12.0 to +14.0 deg(C=1,MeOH) |
Properties (reference)
| Melting Point | 146 °C |
| Specific Rotation | 13° (C=1,MeOH) |
| Solubility in water | Practically insoluble |
| Solubility (slightly sol. in) | Methanol |
| Solubility (very slightly) | Ethanol |
| Solubility (insoluble in) | Heptane |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | NP6333500 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
A Selective Serotonin Reuptake Inhibitor (SSRI), (S)-Citalopram
(S)-Citalopram is a selective serotonin reuptake inhibitor (SSRI), the active S-enantiomer of citalopram [C2370]. Some reports have been suggested that the R-citalopram in citalopram counteracts the effect of the
S-enantiomer.
S-enantiomer.
References
- The pharmacological effect of citalopram resides in the (S)-(+)-enantiomer
- Second-generation SSRIs: human monoamine transporter binding profile of Escitalopram and R-fluoxetine
- Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities
- Escitalopram versus citalopram: the surprising role of the R-enantiomer
- The Two Enantiomers of Citalopram Bind to the Human Serotonin Transporter in Reversed Orientations
- Determination of citalopram and escitalopram together with their active main metabolites desmethyl(es-)citalopram in human serum by column-switching high performance liquid chromatography (HPLC) and spectrophotometric detection
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