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CAS RN: 53956-04-0 | Product Number: G0151
Monoammonium Glycyrrhizinate Hydrate
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Purity: >75.0%(HPLC)
Synonyms:
- Glycyrrhizic Acid Monoammonium Salt Hydrate
- Glycyrrhizin Monoammonium Salt Hydrate
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
$28.00
|
3 | 1 |
| 25G |
$102.00
|
1 | Contact Us |
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| Product Number | G0151 |
| Purity / Analysis Method | >75.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__4__2H__6__5NO__1__6·xH__2O = 839.97 |
| Physical State (20 deg.C) | Solid |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 53956-04-0 |
| Related CAS RN | 563-96-2 |
| Reaxys Registry Number | 3897076 |
| PubChem Substance ID | 87570349 |
| MDL Number | MFCD00167400 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 75.0 area% |
| Specific rotation [a]20/D | +45.0 to +52.0 deg(C=1.5, 40%EtOH)(calcd.on anh.substance) |
| Water | max. 10.0 % |
Properties (reference)
| Melting Point | 217 °C |
| Specific Rotation | 49° (C=1.5,EtOH) |
GHS
Related Laws:
| RTECS# | LZ6500000 |
Transport Information:
| H.S.code* | 2938.90-000 |
Application
Monoammonium Glycyrrhizinate: An Ammonium Salt of a Triterpenoid Saponin Glycyrrhizin
Monoammonium glycyrrhizinate is an ammonium salt of glycyrrhizin [G0150] which is the major triterpenoid saponin of licorice root (Glycyrrhiza glabra). It has been widely used for the treatment of various inflammatory-based skin diseases. Therefore, its various delivery systems have been reported.1-3) It is also an agonist of the human sweet taste receptor4), and is known to be a natural sweetener. It is dissolved in an organic solvent such as DMSO and dimethyl formamide, and also dissolved in organic solvent-free aqueous buffers relatively stably in a pH range from 7 to 9.5) (The product is for research purpose only.)
References
- 1) Ethosomes for skin delivery of ammonium glycyrrhizinate: In vitro percutaneous permeation through human skin and in vivo anti-inflammatory activity on human volunteers
- 2) Chitosan nanoparticles as a novel delivery system for ammonium glycyrrhizinate
- 3) Anti-inflammatory activity of novel ammonium glycyrrhizinate/niosomes delivery system: Human and murine models
- 4) Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells
- 5) Monoammonium glycyrrhizinate stability in aqueous buffer solutions
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