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CAS RN: 29094-61-9 | Product Number: G0369

Glipizide


Purity: >98.0%(T)(HPLC)
Synonyms:
  • N-[4-(3-Cyclohexylureidosulfonyl)phenethyl]-5-methyl-2-pyrazinecarboxamide
Documents:
1G
$65.00
≥20  Contact Us
5G
$223.00
14   Contact Us

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.


Product Number G0369
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__1H__2__7N__5O__4S = 445.54  
Physical State (20 deg.C) Solid
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 29094-61-9
Reaxys Registry Number 903495
PubChem Substance ID 125307849
SDBS (AIST Spectral DB) 52971
Merck Index (14) 4442
MDL Number

MFCD00072159

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 206 °C
GHS
Related Laws:
RTECS# YS7640000
Transport Information:
H.S.code* 2935.90-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Glipizide: A Sulfonylurea ATP-Dependent K+ Channel Antagonist

Glipizide belongs to sulfonylurea antidiabetics which increase the release of insulin from pancreatic B-cells. Sulfonylurea antidiabetics inhibit ATP-gated K+ channels and thereby cause depolarization of the B-cell membrane. The depolarization leads to activation of voltage-dependent Ca channels and Ca2+ influx into the B-cell, and eventually increases insulin release. In addition, glipizide is characterized by poor solubility in water. Therefore, it has been studied to improve the solubility and bioavailability of drug. (The product is for research purpose only. (The product is for research purpose only.)

References


PubMed Literature


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