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CAS RN: 52-86-8 | Product Number: H0912

Haloperidol


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 4-[4-(4-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
Documents:
5G
$42.00
≥20  ≥20 
25G
$127.00
≥20  ≥20 

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* The storage conditions are subject to change without notice.


Product Number H0912
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__1H__2__3ClFNO__2 = 375.87  
Physical State (20 deg.C) Solid
CAS RN 52-86-8
Reaxys Registry Number 331267
PubChem Substance ID 87571270
SDBS (AIST Spectral DB) 14024
Merck Index (14) 4598
MDL Number

MFCD00051423

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Solubility in Acetic acid almost transparency
Melting point 150.0 to 153.0 °C
Properties (reference)
Melting Point 152 °C
Solubility in water Insoluble
Solubility (soluble in) Benzene,Acetone,Chloroform
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H360 : May damage fertility or the unborn child.
H362 : May cause harm to breast-fed children.
H370 : Causes damage to organs.
H372 : Causes damage to organs through prolonged or repeated exposure.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P263 : Avoid contact during pregnancy/ while nursing.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# EU1575000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
H.S.code* 2933.39-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Haloperidol: A Dopamine Receptor (D2) and a Serotonin Receptor (5-HT2) Antagonist

Haloperidol is a butyrophenone series of neurotransmitter agent. The precise mechanism of action has not been clearly established, but it has been shown to be a dopamine receptor (D2) and a serotonin receptor (5-HT2) antagonist. Therefore, haloperidol is classified as a neuroleptic. Haloperidol is metabolized by several routes including the cytochrome P450 enzyme system (particularly CYP3A4 or CYP2D6). Hence, haloperidol inhibits the metabolism of tricyclic antidepressants such as doxepin hydrochloride [D4626] and imipramine hydrochloride [I0971] , increasing the blood levels of these agents. Haloperidol has no anti-histaminergic or anticholinergic activity. Haloperidol is almost insoluble in water, but is soluble in most organic solvents. (The product is for research purpose only.)

References


PubMed Literature


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