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CAS RN: 24386-93-4 | Product Number: I1156

5-Iodotubercidin


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 7-Deaza-7-iodoadenosine
  • 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • 4-Amino-5-iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine
  • 7-Iodo-7-deazaadenosine
Documents:
200MG
$164.00
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* The storage conditions are subject to change without notice.


Product Number I1156
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__1H__1__3IN__4O__4 = 392.15 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 24386-93-4
Reaxys Registry Number 4543232
MDL Number

MFCD00055131

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Volumetric Analysis) min. 98.0 %
NMR confirm to structure
Properties (reference)
Maximum Absorption Wavelength 284(MeOH) nm
GHS
Related Laws:
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
5-Iodotubercidin: A General Protein Kinase Inhibitor

5-Iodotubercidin is a potent and competitive adenosine protein kinase inhibitor. It has been reported that 5-iodotubercidin inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC, and nucleoside transporter.1-3) 5-iodotubercidin also inhibits LRRK2 (Leucine-rich repeat kinase 2) –G2019S that is a promising therapeutic target for the treatment of Parkinson's disease.4) There is a recent report, that 5-Iodotubercidin inhibits SARS-CoV-2 RNA-dependent RNA polymerase (RdRp).5) (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
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