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CAS RN: 480-10-4 | Product Number: K0079
Kaempferol 3-Glucoside
Purity: >92.0%(HPLC)(qNMR)
Synonyms:
- Astragalin
- Kaempferol 3-β-D-Glucopyranoside
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl β-D-Glucopyranoside
Product Documents:
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| Product Number | K0079 |
Purity / Analysis Method
|
>92.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__1H__2__0O__1__1 = 448.38 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 480-10-4 |
| Reaxys Registry Number | 100568 |
| MDL Number | MFCD00075932 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 92.0 area% |
| Purity(qNMR) | min. 92.0 % |
| Melting point | 212.0 to 216.0 °C |
| Water | max. 8.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 214 °C |
GHS
Related Laws:
| RTECS# | DJ3080000 |
Transport Information:
| H.S.code* | 2940.00-000 |
Application
Kaempferol-3-Glucoside: A Flavonoid with Anti-Inflammatory and Antioxidant Activities
Kaempferol-3-glucoside (or astragalin) is a flavonoid with anti-inflammatory and antioxidant activities found in persimmon leaves and green tea seeds. There are reports that kaempferol-3-glucoside promotes apoptosis and attenuates the growth of tumor cells by mediating the NF-κB, PI3K/AKT, MAPK, and JAK/STAT signaling pathways. (The product is for research purpose only.)
References
- Inhibitory effect of astragalin on expression of lipopolysaccharide-induced inflammatory mediators through NF-κB in macrophages
- Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-κB signaling pathway
- Astragalin suppresses inflammatory responses via down-regulation of NF-κB signaling pathway in lipopolysaccharide-induced mastitis in a murine model
- Astragalin: a food-origin flavonoid with therapeutic effect for multiple diseases (a review)
- A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: Application to a pharmacokinetic study of total flavonoids from mulberry leaves
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