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CAS RN: 100986-85-4 | Product Number: L0193

Levofloxacin


Purity: >98.0%(HPLC)
Synonyms:
Documents:
5G
$67.00
≥20  ≥20 
25G
$192.00
4   ≥20 

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* The storage conditions are subject to change without notice.


Product Number L0193
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__8H__2__0FN__3O__4 = 361.37  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 100986-85-4
Reaxys Registry Number 5385660
PubChem Substance ID 87558890
SDBS (AIST Spectral DB) 51758
Merck Index (14) 6771
MDL Number

MFCD00865049

Specifications
Appearance Light orange to Yellow to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 96.0 %
Melting point 222.0 to 230.0 °C
Specific rotation [a]20/D -63.0 to -70.0 deg(C=5, CHCl3)
Properties (reference)
Melting Point 224 °C
Specific Rotation -66° (C=5,CHCl3)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# UU8815550
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Levofloxacin: The Active (S)-(-)-Enantiomer of Ofloxacin, Fluoroquinolone Antimicrobial

Levofloxacin, a synthetic fluoroquinolone antimicrobial, is the active (S)-(-)-enantiomer of the racemic drug substance ofloxacin [O0403]. Levofloxacin has broad-spectrum bactericidal activity against most Gram-negative bacteria, many Gram-positive bacteria and some anaerobes. The mechanism of action of ofloxacin (and other fluoroquinolone) involves inhibition of bacterial topoisomerase IV and DNA gyrase (topoisomerases II), enzymes required for DNA replication, transcription, repair and recombination. For your reference, [L0238] is a key synthetic intermediate of levofloxacin. (The product is for research purpose only.)

References


PubMed Literature


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