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CAS RN: 1180-71-8 | Product Number: L0258

Limonin


Purity: >95.0%(HPLC)
Synonyms:
Documents:
100MG
$139.00
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1G
$705.00
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* The storage conditions are subject to change without notice.


Product Number L0258
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__2__6H__3__0O__8 = 470.52  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 1180-71-8
Reaxys Registry Number 1695716
PubChem Substance ID 253661951
Merck Index (14) 5494
MDL Number

MFCD00075922

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC)(CAD) min. 95.0 area%
Specific rotation [a]20/D -116 to -120 deg(C=1, Acetone)
Properties (reference)
Melting Point 298 °C
Specific Rotation -117° (C=1,Acetone)
Maximum Absorption Wavelength 285 nm
Solubility in water Insoluble
Solubility (soluble in) Acetone,Tetrahydrofuran
Solubility (very slightly) Ether,Alcohol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
RTECS# RR1122000
Transport Information:
H.S.code* 2932.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Limonin: A Chemically-Induced Carcinogenesis Inhibitor and a HIV-1 Replication Inhibitor

Limonin is a non-volatile triterpeneis which is one of two major bitter principles in citrus juice, especially in grapefruit juice. Limonin has been found to inhibit chemical induced carcinogenesis. Limonin is an inducer of glutathione S-transferase, a major detoxifying enzyme system. Additionally, limonin has been reported to inhibit in vitro HIV-1 protease activity.

References


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