Product Document Searching Made Easy by 2D Code! | TCI Life Science News July 2026 | [Product Highlights] Mitochondrial Membrane Potential... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 97792-45-5 | Product Number: L0272
Lappaconitine Hydrobromide
×
Purity: >95.0%(N)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
$109.00
|
0 | 10 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | L0272 |
Purity / Analysis Method 
|
>95.0%(N) |
| Molecular Formula / Molecular Weight | C__3__2H__4__4N__2O__8·HBr = 665.62 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 97792-45-5 |
| Related CAS RN
|
32854-75-4 |
| Reaxys Registry Number | 3868594 |
| PubChem Substance ID | 253662089 |
| MDL Number | MFCD00171334 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 93.0 area% |
| Purity(with Total Nitrogen) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 222 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | AR5569600 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | II |
| H.S.code* | 2939.79-000 |
Application
Lappaconitine hydrobromide: A Diterpene Alkaloid Working as an Inhibitor of Voltage-Dependent Sodium Channels
Lappaconitine hydrobromide is a diterpene alkaloid extracted from roots of Aconitum sinomantanum. It is a non-narcotic central nervous system analgesic. Lappaconitine also has antiarrhythmic and anti-inflammatory effect. Lappaconitine works as an inhibitor of tetrodotoxin-sensitive, voltage-dependent sodium channels. On the other hand, lappaconitine is reported as an organocatalyst for asymmetric α-hydroxylation of β-keto esters. (The product is for research purpose only.)
References
- Pharmacological studies on lappaconitine: antinociception and inhibition of the spinal action of substance P and somatostatin
- Cardiac effects of lappaconitine and N-deacetyllappaconitine. Two diterpenoid alkaloids from plants of the Aconitum and Delphinium species
- Mode of antinociceptive and toxic action of alkaloids of Aconitum spec
- Diterpenoid alkaloids as a new class of antiarrhythmic agents. Structure-activity relationship
- Irreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine
- Pharmacokinetic study of lappaconitine hydrobromide in mice by LC-MS
- Lappaconitine-catalyzed asymmetric α-hydroxylation of β-keto esters: a Brønsted base organocatalyst developed from terpenoid alkaloids
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.