Maximum quantity allowed is 999
Please select the quantity
CAS RN: 54-11-5 | Product Number: N0079
Nicotine
×
Purity: >95.0%(GC)(T)
Synonyms:
- (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25ML |
$70.00
|
21 | 10 | It can be shipped in about 2 weeks after ordering | |
| 100ML |
$170.00
|
3 | 13 | It can be shipped in about 2 weeks after ordering | |
| 500ML |
$573.00
|
20 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | N0079 |
Purity / Analysis Method 
|
>95.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4N__2 = 162.24 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic |
| CAS RN | 54-11-5 |
| Reaxys Registry Number | 82109 |
| PubChem Substance ID | 87573472 |
| SDBS (AIST Spectral DB) | 6729 |
| Merck Index (14) | 6524 |
| MDL Number | MFCD00006369 |
Specifications
| Appearance | Colorless to Red to Green clear liquid |
| Purity(GC) | min. 95.0 % |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Specific rotation [a]20/D | -160 to -173 deg(C=10, Acetone) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | -80 °C |
| Boiling Point | 91 °C/3 mmHg |
| Flash point | 95 °C |
| Specific Gravity (20/20) | 1.02 |
| Specific Rotation | -167° (C=10,Acetone) |
| Refractive Index | 1.53 |
| Solubility in water | Completely miscible |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H361 : Suspected of damaging fertility or the unborn child. H370 : Causes damage to organs. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P262 : Do not get in eyes, on skin, or on clothing. P202 : Do not handle until all safety precautions have been read and understood. P260 : Do not breathe mist or vapours. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P391 : Collect spillage. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| RTECS# | QS5250000 |
Transport Information:
| UN Number | UN1654 |
| Class | 6.1 |
| Packing Group | II |
| H.S.code* | 2939.79-000 |
Application
Nicotine: A Nicotinic Acetylcholine Receptors (nAChRs) Agonist
Nicotine (or (-)-(S)-nicotine) is an alkaloid and natural insecticide that acts as an anti-herbivore chemical in tobacco plants. Nicotine acts as a nicotinic acetylcholine receptors (nAChRs) agonist. nAChRs are a family of ligand-gated ion channels. Recent studies have shown that nicotine activates neuronal nAChRs in peripheral and central nervous systems leading to depolarization of cell membranes and elevation of intracellular calcium levels, which are considered to cause stimulation of neurotransmitter release, synaptic transmission, intracellular signal transduction and gene expression.1) Nicotine is also used as a probe agent for phenotyping cytochrome P450 2A6 (CYP2A6) which is involved in the metabolism of nicotine.2) (The product is for research purpose only.)
References
- 1) Mammalian nicotinic acetylcholine receptors: from structure to function (a review)
- 2) Metabolism and disposition kinetics of nicotine (a review)
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.