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CAS RN: 318-98-9 | Product Number: P0995

Propranolol Hydrochloride


Purity: >99.0%(T)(HPLC)
Synonyms:
  • 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol Hydrochloride
Documents:
25G
$113.00
Contact Us 9  
250G
$661.00
10   6  

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* The storage conditions are subject to change without notice.


Product Number P0995
Purity / Analysis Method >99.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__2__1NO__2·HCl = 295.81  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 318-98-9
Related CAS RN 525-66-6
Reaxys Registry Number 4164259
PubChem Substance ID 87575108
Merck Index (14) 7840
MDL Number

MFCD00012558

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 99.0 area%
Purity(Nonaqueous Titration) min. 99.0 %
Melting point 163.0 to 168.0 °C
Solubility in hot Water almost transparency
Properties (reference)
Melting Point 166 °C
Solubility in water Soluble
Solubility (soluble in) Alcohol
Solubility (insoluble in) Ether,Benzene
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# UB7525000
Transport Information:
H.S.code* 2922.19-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Propranolol Hydrochloride: A Non-Selective and Catecholamine Competitive β-Adrenergic Receptor Antagonist

Propranolol hydrochloride is a non-selective and competitive catecholamine β-adrenergic receptor antagonist. Propranolol blocks β1 (myocardial)- and β2(pulmonary, vascular and uterine)-adrenergic receptor site. There are two enantiomers of propranolol, and it is reported that the S-enantiomer blocks β-adrenergic receptors. The mechanism of the antihypertensive effects of propranolol has not been clearly established. However, propranolol may reduce the oxygen requirement of the heart at any level of effort by blocking catecholamine (such as dopamine [A0305], noradrenaline [A0906] and adrenaline [A0173])-induced increases in the heart rate, systolic blood pressure and the velocity and extent of myocardial contraction. (The product is for research purpose only.)

References


Application
Reagent for cardiomyopathy model

References


PubMed Literature


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