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CAS RN: 58-39-9 | Product Number: P1970

Perphenazine


Purity: >97.0%(T)(HPLC)
Synonyms:
  • 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
  • 4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
Documents:
5G
$99.00
8   18  
25G
$347.00
1   2  

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Product Number P1970
Purity / Analysis Method >97.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__1H__2__6ClN__3OS = 403.97  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 58-39-9
Reaxys Registry Number 54730
PubChem Substance ID 253660321
Merck Index (14) 7183
MDL Number

MFCD00056798

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Nonaqueous Titration) min. 97.0 %
Melting point 95.0 to 99.0 °C
Properties (reference)
Melting Point 97 °C
Solubility in water Insoluble
Degree of solubility in water 28.3 mg/l   24 °C
Solubility (very soluble in) Chloroform
Solubility (soluble in) Acetone,Ethanol
Solubility (very slightly) Ether
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# TL7175000
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Perphenazine: A Classical Phenothiazine Typical Antipsychotic

Perphenazine is a classical phenothiazine typical antipsychotic with a potency similar to haloperidol [H0912], a dopamine antagonist. It is extensively metabolized in the liver to a number of metabolites. The pharmacokinetics of perphenazine is mediated by cytochrome P450 2D6 (CYP2D6) and thus is subject to genetic polymorphism. It induces cleft palate in mice fetuses. (The product is for research purpose only.)

References


PubMed Literature


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