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CAS RN: 68890-66-4 | Product Number: P2178
Piroctone Olamine
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone Ethanolamine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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|---|---|---|---|---|---|
| 1G |
$88.00
|
3 | 0 | Contact Us | |
| 5G |
$292.00
|
16 | 0 | Contact Us |
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| Product Number | P2178 |
Purity / Analysis Method 
|
>97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__2__3NO__2·C__2H__7NO = 298.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 68890-66-4 |
| Related CAS RN
|
50650-76-5 |
| Reaxys Registry Number | 7503297 |
| PubChem Substance ID | 253662076 |
| Merck Index (14) | 7502 |
| MDL Number | MFCD01690792 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 134.0 to 138.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 136 °C |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H315 : Causes skin irritation. H318 : Causes serious eye damage. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
Related Laws:
| RTECS# | UU7786150 |
Transport Information:
| H.S.code* | 2933.79-000 |
Application
Piroctone olamine: A Hydroxypyridone Antimycotic
Piroctone olamine belongs to the class of hydroxypyridone antimycotics. The mode of action of hydroxypyridone antimycotics is not fully understood. It is often used as an antidandruff agent with shampoo and etc. (The product is for research purpose only.)
References
- Antidandruff hair tonic containing piroctone olamine
- E. Futterer, Cosmet. Toiletries 1988, 103, 49-50, 52.
- The antidandruff efficacy of a shampoo containing piroctone olamine and salicylic acid in comparison to that of a zinc phyrithione shampoo
- In vitro antimycotic activity and nail permeation models of a piroctone olamine (octopirox) containing transungual water soluble technology
- In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans
- Increased in vivo efficacy of lenalidomide by addition of piroctone olamine
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