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CAS RN: 330786-25-9 | Product Number: P2687

PCI 29732


Purity: >98.0%(HPLC)
Synonyms:
  • 1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Documents:
10MG
$207.00
8   13  
50MG
$717.00
8   13  

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.


Product Number P2687
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__2H__2__1N__5O = 371.44 
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 330786-25-9
Reaxys Registry Number 23187675
MDL Number

MFCD25976874

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 18.00 to 19.50 %
Melting point 141.0 to 145.0 °C
Properties (reference)
Melting Point 143 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
Transport Information:
H.S.code* 2933.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
PCI29732: A Highly Selective Irreversible Inhibitor for Bruton's Tyrosine Kinase (Btk)

PCI29732 is a selective irreversible inhibitor for Bruton's tyrosine kinase (Btk) which is a cytoplasmic tyrosine kinase important in B-lymphocyte development, differentiation, and signaling.1) In addition, the study recently has demonstrated that PCI29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2 and enhances the anti-tumor efficacy of substrate chemotherapeutic agents.2) (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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Other Documents

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