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CAS RN: 129101-54-8 | Product Number: R0093

Rivastigmine L-Tartrate

Purity: >98.0%(T)(HPLC)
  • 3-[(S)-1-(Dimethylamino)ethyl]phenyl N-Ethyl-N-methylcarbamate L-Tartrate
  • N-Ethyl-N-methylcarbamic Acid 3-[(S)-1-(Dimethylamino)ethyl]phenyl Ester L-Tartrate
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Product Number R0093
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__4H__2__2N__2O__2·C__4H__6O__6 = 400.43 
Physical State (20 deg.C) Solid
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 129101-54-8
Related CAS RN 123441-03-2
PubChem Substance ID 135727179
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 124.0 to 128.0 °C
Specific rotation [a]20/D +4.0 to +7.0 deg(C=5, methanol)
Properties (reference)
Melting Point 126 °C
Specific Rotation 5° (C=5,MeOH)
Solubility (soluble in) Methanol
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# FA9550000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
H.S.code* 2924.29-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Rivastigmine Tartrate: A Dual Inhibitor of Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE)

Rivastigmine tartrate is an inhibitor of two cholinesterase enzymes, acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Rivastigmine activates central cholinergic nervous system by increasing the concentration of acetylcholine (ACh) in brain through reversible inhibition of its hydrolysis by AChE and BuChE. For comparison, another cholinesterase inhibitor, donepezil hydrochloride [D4099] shows high selectivity for AChE over BuChE.. Rivastigmine tartrate is used for the treatment of Alzheimer’s disease. For your reference, [D5326] is a synthetic intermediate of rivastigmine L-tartrate. (The product is for research purpose only.)


PubMed Literature

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