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CAS RN: 3366-95-8 | Product Number: S0911
Secnidazole
×
Purity: >98.0%(GC)
Synonyms:
- 1-(2-Methyl-5-nitroimidazol-1-yl)-2-propanol
Product Documents:
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| 1G |
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| 5G |
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| Product Number | S0911 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__7H__1__1N__3O__3 = 185.18 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 3366-95-8 |
| Reaxys Registry Number | 612717 |
| PubChem Substance ID | 253662365 |
| Merck Index (14) | 8419 |
| MDL Number | MFCD00864656 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 72.0 to 76.0 °C |
| Water | max. 3.0 % |
Properties (reference)
| Melting Point | 74 °C |
| Maximum Absorption Wavelength | 319 nm (H__2O) |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.29-000 |
Application
Secnidazole: A Synthetic 5-Nitroimidazole Antibiotic
Secnidazole is a synthetic 5-nitroimidazole antibiotic such as metronidazole [M0924] and tinidazole [T3058]. These antibiotics share a common spectrum of activity against micro-organisms. They possess selective activity against many anaerobic Gram-positive and Gram-negative bacteria and protozoa. And they appear particularly effective in the treatment of, giardiasis, trichomoniasis and bacterial vaginosis. They can also be used to treat Helicobacter pylori infection. Secnidazole has been reported it as a corrosion inhibitor for mild steel in hydrochloric acid solution. (The product is for research purpose only.)
References
- Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis
- Metabolism of a 5-nitroimidazole in susceptible and resistant isogenic strains of Bacteroides fragilis
- Lansoprazole [L0233] and secnidazole with clarithromycin [C2220], amoxicillin [A2099] or pefloxacin in the eradication of Helicobacter pylori in a developing country
- Rapid and selective analysis of secnidazole in human plasma using high-performance liquid chromatography with ultraviolet detection
- Inhibitive properties, thermodynamic characterization and quantum chemical studies of secnidazole on mild steel corrosion in acidic medium
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