Maximum quantity allowed is 999
Please select the quantity
CAS RN: 1885-46-7 | Product Number: T4382
Difluoromethyl Trifluoromethanesulfonate
×
Purity: >98.0%(GC)
Synonyms:
- Difluoromethyl Triflate
- Trifluoromethanesulfonic Acid Difluoromethyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$55.00
|
1 | 0 | Contact Us | |
| 5G |
$199.00
|
0 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | T4382 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2HF__5O__3S = 200.08 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 1885-46-7 |
| Reaxys Registry Number | 1870187 |
| MDL Number | MFCD28054469 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 49 °C |
| Flash point | 57 °C |
| Specific Gravity (20/20) | 1.6 |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H314 : Causes severe skin burns and eye damage. H226 : Flammable liquid and vapor. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P240 : Ground and bond container and receiving equipment. P210 : Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 : Keep container tightly closed. P243 : Take action to prevent static discharges. P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 : Use non-sparking tools. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P403 + P235 : Store in a well-ventilated place. Keep cool. P405 : Store locked up. |
Related Laws:
Transport Information:
| UN Number | UN2920 |
| Class | 8 / 3 |
| Packing Group | II |
| H.S.code* | 2905.59-000 |
Application
TCI Practical Example: Difluoromethoxylation of Aromatic Alcohols Using a Novel Difluoromethoxylating Agent
Used Chemicals
- Difluoromethyl Trifluoromethanesulfonate [T4382]
- 2-Nitrophenol [N0219]
- Potassium Hydroxide
- Acetonitrile
- Water
Procedure
6 mol/L Potassium hydroxide aqueous solution (1.0 mL, 6 mmol) was added to a solution of 2-nitrophenol (70 mg, 0.50 mmol) in acetonitrile (1.0 mL) and stirred vigorously at room temperature. Then, difluoromethyl trifluoromethanesulfonate (300 mg, 1.50 mmol) was added to the mixture in one shot and stirred vigorously for 2 minutes at room temperature. The reaction mixture was extracted with diethyl ether (10 mL x 2), dried over sodium sulfate (10 g), and concentrated under reduced pressure to afford 1-(difluoromethoxy)-2-nitrobenzene (93.3 mg, 98% yield) as a colorless oil.
Experimenter’s Comments
- The reaction was monitored by TLC (hexane:ethyl acetate = 3:1, Rf = 0.5) and UPLC-MS.
- This reagent is highly volatile, so prompt handling was required.
- Since high-purity product was obtained after the completion of separation process, no further purification steps were required.
Analytical Data
1-(Difluoromethoxy)-2-nitrobenzene
1H NMR (400 MHz, CDCl3); δ 7.93 (d, J = 8.0 Hz, 1H), 7.63 (t, J = 7.2 Hz, 1H), 7.40 (m, 2H), 6.63 (t, J = 73.2 Hz, 1H)
Lead Reference
- Synthesis of Difluoromethyl Ethers with Difluoromethyltriflate
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.