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CAS RN: 211555-04-3 | Product Number: W0013


Purity: >98.0%(HPLC)
  • 2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol
7   ≥20 
8   ≥20 

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* The storage conditions are subject to change without notice.

Product Number W0013
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__6H__1__4BrN__3O__3 = 376.21  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 211555-04-3
Reaxys Registry Number 8787580
MDL Number


Appearance White to Yellow to Orange powder to crystal
Purity(HPLC) min. 98.0 area%
Melting point 228.0 to 232.0 °C
Elemental analysis(Nitrogen) 10.50 to 11.50 %
Properties (reference)
Melting Point 230 °C
Maximum Absorption Wavelength 335(MeOH) nm
Hazard Statements H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
Related Laws:
Transport Information:
H.S.code* 2933.59-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
WHI-P 154: A Potent Janus-Associated Kinase 3 (JAK3) Inhibitor

WHI-P 154 is a potent Janus-associated kinase 3 (JAK3) inhibitor that displays no activity at JAK1 or JAK2. JAK3 is a cytoplasmic protein tyrosine kinase that functions in the initiation of cytokine-triggered signal transduction by catalyzing the phosphorylation of signal transduction and activators of transcription (STAT). The phosphorylated SATAs are translocated to the nucleus to activate target genes. WHI-P 154 is cytotoxic human glioblastoma cells. Recent reports have indicated that JAK3 is expressed in lymphoid cells and is involved in the signaling of T cell functions. Therefore, the development of a selective JAK3 inhibitor has been shown to have a potential benefit in the treatment of autoimmune disorders. (The product is for research purpose only.)


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