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CAS RN: 1092679-51-0 | Product Number: W0016
WAY-100635 Maleate
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Purity: >98.0%(HPLC)
Synonyms:
- N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-N-(pyridin-2-yl)cyclohexanecarboxamide Maleate
Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 10MG |
$197.00
|
1 | Contact Us |
| 50MG |
$692.00
|
≥20 | 1 |
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| Product Number | W0016 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__4N__4O__2·C__4H__4O__4 = 538.65 |
| Physical State (20 deg.C) | Solid |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic |
| CAS RN | 1092679-51-0 |
| MDL Number | MFCD01321056 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
Properties (reference)
GHS
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Transport Information:
| H.S.code* | 2933.59-000 |
Application
WAY-100635: A 5-HT1A Receptor Antagonist and a Dopamine D4 Receptor Agonist
WAY-100635 was originally reported as a selective 5-HT1A receptor antagonist with 100-fold selectivity against other 5-HT subtypes.1,2) However, subsequent research showed that it also acts as a potent dopamine D4 receptor agonist.3,4)
References
- 1) Synthesis and evaluation of 4-(2'-methoxyphenyl)-1-[2'-[N-(2''-pyridinyl)- p-iodobenzamido]ethyl]piperazine (p-MPPI): A new iodinated 5-HT1A ligand
- 2) A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635
- 3) WAY-100635 is a potent dopamine D4 receptor agonist
- 4) WAY-100635 has high selectivity for serotonin 5-HT1A versus dopamine D4 receptor
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