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CAS RN: 26615-21-4 | Product Number: Z0054
Zotepine
Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-[(8-Chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
$253.00
|
14 | 0 | Contact Us |
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| Product Number | Z0054 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__1__8ClNOS = 331.86 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 26615-21-4 |
| Reaxys Registry Number | 1435710 |
| MDL Number | MFCD00868143 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 91.0 to 95.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 93 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Dioxane |
| Solubility (slightly sol. in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dust. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | HQ2541700 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Zotepine: A Dibenzothiepine Tricyclic Serotonin and Dopamine Antagonist
Zotepine is a dibenzothiepine tricyclic serotonin and dopamine antagonist that has a high affinity for serotonin 5-HT2A and 5-HT2C, and dopamine D1 and D2 receptors. Zotepine activities are also related to the inhibition of noradrenaline reuptake. In clinical, zotepine has been used as an antipsychotic agent. (The product is for research purpose only.)
References
- Zotepine: preclinical tests predict antipsychotic efficacy and an atypical profile
- Zotepine: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of schizophrenia
- Selective separation and detection of zotepine and mass spectral characterization of degradants by LC-MS/MS/QTOF
- Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, single-sample approach
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Specifications
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