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Published TCIMAIL newest issue No.198
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CAS RN: 51-83-2 | Product Number: C0596
Carbamylcholine Chloride
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Purity: >98.0%(T)
Synonyms:
- Carbachol
- (2-Carbamoyloxyethyl)trimethylammonium Chloride
- Choline Chloride Carbamate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 10G |
104,00 €
|
2 | 22 |
| 25G |
187,00 €
|
24 | ≥100 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C0596 |
Purity / Analysis Method 
|
>98.0%(T) |
| Molecular Formula / Molecular Weight | C__6H__1__5ClN__2O__2 = 182.65 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 51-83-2 |
| Reaxys Registry Number | 3917459 |
| PubChem Substance ID | 87565693 |
| SDBS (AIST Spectral DB) | 4583 |
| Merck Index (14) | 1779 |
| MDL Number | MFCD00012011 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Solubility in Water | almost transparency |
Properties (reference)
| Melting Point | 189 °C |
| Solubility (slightly sol. in) | Alcohol |
| Solubility (insoluble in) | Acetone, Ether, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 200-127-3 |
| RTECS# | GA0875000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2924297099 |
Application
Reagent for dysuria model
References
- TRK-380, a novel selective human β3-adrenoceptor agonist, ameliorates formalin-induced pollakiuria in rats and carbachol-induced bladder contraction in dogs
- Inhibitory effects of salviae miltiorrhizae radix (danshen) and puerariae lobatae radix (gegen) in carbachol-induced rat detrusor smooth muscle contractility
- W. Liang, I. W. Teong J. C. Koon, C. B. Lau, K. P. Fung, P. C. Leung, Int. J. Physiol. Pathophysiol. Pharmacol. 2012, 4, 36.
- Frusemide potentiates acetylcholine and carbachol in contracting the rat urinary bladder
- J. N. Okpukpara, P. A. Akah, J. Pharm. Pharmacol. 1990, 42, 597.
- Carbachol-induced sustained tonic contraction of rat detrusor muscle
- Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladder
- Inhibitory effects of various L-type and T-type calcium antagonists on electrically generated, potassium-induced and carbachol-induced contractions of porcine detrusor muscle
- Carbachol-induced rabbit bladder smooth muscle contraction: roles of protein kinase C and Rho kinase
- Variations in carbachol- and ATP-induced contractions of the rat detrusor: effects of gender, mucosa and contractile direction
- The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels
Application
Reagent for asthenopia model
References
- Nitric oxide relaxes bovine ciliary muscle contracted by carbachol through elevation of cyclic GMP
- Effects of nitric oxide donors and nitric oxide synthase substrates on ciliary muscle contracted by carbachol and endothelin for possible use in myopia prevention
- C. Beauregard, Q. Liu, G. C. Chiou, J. Ocul. Pharmacol. Ther. 2001, 17, 1.
- Effects of phorbol ester on carbachol-induced contraction in bovine ciliary muscle: possible involvement of protein kinase C
- Inhibitory effects of amlexanox on carbachol-induced contractions of rabbit ciliary muscle and guinea-pig taenia caecum
- N. Watanabe, Y. Tominaga, K. Mizutani, T. Ogawa, H. Tsunobuchi-Ushijima, Y. Gomi, J. Pharm. Pharmacol. 2000, 52, 1377.
Application
Reagent for gastropathy (gastric secretion) model
Reference
- Inhibition of gastric acid secretion by cholinergic stimulation of the lateral hypothalamic area
- J. A. Gontijo, C. R. Silva-Netto, M. R. Furtado, Braz. J. Med. Biol. Res. 1990, 23, 361.
PubMed Literature
Product Articles
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Safety Data Sheet (SDS)
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Specifications
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