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Published TCIMAIL newest issue No.198
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CAS RN: 6882-68-4 | Product Number: M3093
Sophoridine
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Purity: >98.0%(GC)(T)
Synonyms:
- (5β)-Matridin-15-one
- (7aR,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 50MG |
€52.00
|
Contact Us | 2 |
| 250MG |
€187.00
|
Contact Us | 13 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M3093 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__5H__2__4N__2O = 248.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 6882-68-4 |
| Reaxys Registry Number | 85850 |
| PubChem Substance ID | 468592265 |
| MDL Number | MFCD00238686 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 107.0 to 111.0 °C |
| Specific rotation [a]20/D | -66.0 to -73.0 deg(C=1, ethanol) |
Properties (reference)
| Melting Point | 109 °C |
| Specific Rotation | -70° (C=1,EtOH) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | WG1250000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939799090 |
Application
Sophoridine: A Valuable Bioactive Quinolizidine Alkaloid
Sophoridine is quinolizidine alkaloid which is an active component of Chinese traditional medicines, which exists in the stems and leafs of leguminous plant Sophora alopecuroides L. and the roots of Sophora alopecuroides Ait. It has been reported that it has anti-tumor,1) anti-arrhythmia,2) anti-viral,3) and anti-inflammatory and immune suppression4) activities. (The product is for research purpose only.)
References
- 1) In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait
- 2) Anti-arrhythmic effects of sophoridine and oxysophoridine
- 3) Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats
- 4) Sophocarpine and matrine inhibit the production of TNF-α and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice
- 5) Determination of quinolizidine alkaloids in traditional Chinese herbal drugs by nonaqueous capillary electrophoresis
- 6) Simultaneous determination of matrine, sophoridine and oxymatrine in Sophora Flavescens Ait. by high performance liquid chromatography
Product Documents (Note: Some products will not have analytical charts available.)
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