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CAS RN: 26471-62-5 | Product Number: T0264
Tolylene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
×
Purity: >98.0%(GC)
Synonyms:
- Toluene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 25G |
€17.00
|
1 | 23 |
| 500G |
€54.00
|
6 | ≥100 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
[Handling Note]
This product may deposit some white solids during storage. Please use all of the material as soon as possible upon receiving it.
| Product Number | T0264 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__9H__6N__2O__2 = 174.16 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 26471-62-5 |
| Reaxys Registry Number | 8188352 |
| PubChem Substance ID | 87576244 |
| MDL Number | MFCD01778251 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 98.0 %(total of isomer) |
Properties (reference)
| Melting Point | 14 °C |
| Boiling Point | 251 °C |
| Flash point | 137 °C |
| Specific Gravity (20/20) | 1.22 |
| Refractive Index | 1.57 |
| Solubility (miscible with) | Ether, Benzene, Acetone |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H330 : Fatal if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. H351 : Suspected of causing cancer. H335 : May cause respiratory irritation. H412 : Harmful to aquatic life with long lasting effects. |
| Precautionary Statements | P260 : Do not breathe mist or vapours. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. |
Related Laws:
| EC Number | 247-722-4 |
| RTECS# | NQ9490000 |
Transport Information:
| UN Number | UN2078 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2929100090 |
Application
Reagent for airway hyperresponsiveness (asthma) model
References
- The development of an animal model for TDI asthma
- M. H. Karol, Bull. Eur. Physiopathol. Respir. 1987, 23, 571.
- An asthma model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate
- Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI)
- A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor
- Y. C. Lee, C. H. Song, H. B. Lee, J. L. Oh, Y. K. Rhee, H. S. Park, G. Y. Koh, J. Allergy Clin. Immunol. 2001, 108, 1021.
- Mesenchymal stem cell transfer suppresses airway remodeling in a toluene diisocyanate-induced murine asthma model
PubMed Literature
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