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CAS RN: | Product Number: A3251
Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)
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Product Information
Volume/Quantity : 0.1 mg
Product Form : Purified mouse monoclonal antibody/IgM
Buffer : Phosphate buffered-saline (PBS)
Preparation : The antibody is purified from mouse ascites fluid.
Preservative : 0.05% Sodium azide
Stabilizer : None
Immunogen : Salmonella minnesota strain R595 coated with pure synthetic glycolipid
Specificity : 6-sulfo LacNAc and 6-sulfo Lewis x
Clone Name : AG105
Application
ELISA, Flow cytometry, Immunohistochemistry, Western blot, TLC-immunostaining
Storage
Store at －20 ºC to －80 ºC (Preferably at －80 ºC). It is not recommended storing at 4 ºC. Avoid repeated freezing and thawing.
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| Product Number | A3251 |
| Physical State (20 deg.C) | Liquid |
Storage Temperature 
|
Frozen (-80°C) |
| Condition to Avoid | Heat Sensitive |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Titer(ELISA) | to pass test |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 3002.19-000 |
Application
Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)
References
- Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer.
- M. Izawa, K. Kumamoto, C. Mitsuoka, A. Kanamori, K. Ohmori, H. Ishida, S. Nakamura, K. Kurata-Miura, K. Sasaki, T Nishi, R Kannagi, Cancer Res. 2000, 60, 1410.
- 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells.
- K. Schäkel, R. Kannagi, B. Kniep, Y. Goto, C. Mitsuoka, J. Zwirner, A. Soruri, M. von Kietzell, E. P. Rieber, Immunity 2002, 17, 289.
- TNF-α increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
- Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-α.
- Anti-oligosaccharide antibodies as tools for studying sulfated sialoglycoconjugate ligands for siglecs and selectins
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