Maintenance Notice (3:15 AM - 2:55 PM May 24, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Materials Science News May 2025 | [Product Highlights] Endogenous Biotin-Blocking Reagent... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 188062-50-2 | Product Number: A3532
Abacavir Sulfate
×
![]()
×
Purity: >95.0%(T)(HPLC)
Synonyms:
- Abacavir Hemisulfate
- [(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol Hemisulfate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
NT$4,200
|
20 | 3 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | A3532 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__8H__3__6N__1__2O__2·H__2O__4S = 670.75 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 188062-50-2 |
| Reaxys Registry Number | 10402665 |
| MDL Number | MFCD04112763 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Volumetric Analysis) | min. 95.0 % |
| Specific rotation | -38.0 to -42.0 deg(C=0.5, methanol) |
| Water | max. 1.0 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility in water | Soluble |
| Degree of solubility in water | 77,000 mg/l 25 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. H341 : Suspected of causing genetic defects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
Transport Information:
| H.S.code* | 2933.59-000 |
Application
Abacavir Sulfate: A Nucleoside Analog Reverse Transcriptase Inhibitor (RTI)
Abacavir sulfate (1592U89 sulfate), a sulfate salt form of abacavir [A2694], is a nucleoside reverse transcriptase inhibitor (RTI) that inhibits HIV-1 in vitro with a potency similar to that of zidovudine [A2052]. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP) which is an analogue of deoxyguanosine-5’-triphosphate (dGTP). CBV-TP is incorporated into the virus DNA strand in place of dGTP, and inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP. (The product is for research purpose only.)
References
- 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity
- Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89
- Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89
- Separation and characterization of forced degradation products of abacavir sulphate by LC–MS/MS
- Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.