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CAS RN: 427-51-0 | Product Number: C2942
Cyproterone Acetate

Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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200MG |
NT$3,990
|
1 | 3 | Contact Us | |
1G |
NT$13,902
|
4 | 0 | Contact Us |
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Product Number | C2942 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__4H__2__9ClO__4 = 416.94 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 427-51-0 |
Reaxys Registry Number | 2342172 |
PubChem Substance ID | 253660432 |
Merck Index (14) | 2774 |
MDL Number | MFCD00864671 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Melting point | 206.0 to 211.0 °C |
Specific rotation [a]20/D | +148.0 to +156.0 deg(C=1, CHCl3) |
NMR | confirm to structure |
Properties (reference)
Melting Point | 209 °C |
Specific Rotation | 152° (C=1,CHCl3) |
Maximum Absorption Wavelength | 281 nm (MeOH) |
Solubility in water | Insoluble |
Degree of solubility in water | 52 mg/l 25 °C |
Solubility (soluble in) | Methanol |
Solubility (slightly sol. in) | Ethanol |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H360 : May damage fertility or the unborn child. H351 : Suspected of causing cancer. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
RTECS# | GZ2230000 |
Transport Information:
H.S.code* | 2937.29-000 |
Application
Cyproterone Acetate: A Synthetic Progestogen with Antiandrogenic Activity
Cyproterone acetate is a synthetic progestogen, which have antiandrogenic activity. It acts mainly by blocking androgen receptors, but also reduces the activity of skin 5α-reductase in sebaceous glands and hair follicles. It is primarily used in the treatment of androgen-related conditions such as acne, androgen dependent alopecia and prostate cancer. (The product is for research purpose only.)
References
- The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research (a review)
- Antiandrogens: selective androgen receptor modulators (a review)
- Progestogens with antiandrogenic properties (a review)
- Antiandrogens in the treatment of prostate cancer (a review)
PubMed Literature
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