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CAS RN: 143491-57-0 | Product Number: E1007
Emtricitabine
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
NT$1,092
|
20 | 0 | It can be shipped in about 2 weeks after ordering | |
| 250MG |
NT$6,762
|
11 | 17 | It can be shipped in about 2 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | E1007 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__8H__1__0FN__3O__3S = 247.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 143491-57-0 |
| Reaxys Registry Number | 5908714 |
| PubChem Substance ID | 253660241 |
| Merck Index (14) | 3565 |
| MDL Number | MFCD00870151 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 153.0 to 157.0 °C |
| Specific rotation [a]20/D | -137.0 to -143.0 deg(C=0.25, MeOH) |
Properties (reference)
| Melting Point | 155 °C |
| Specific Rotation | -140° (C=0.25,MeOH) |
| Maximum Absorption Wavelength | 280 nm (H__2O) |
| Solubility in water | Soluble |
| Degree of solubility in water | 112 g/l 25 °C |
GHS
Related Laws:
| RTECS# | UW7360500 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Emtricitabine (FTC): a Nucleoside Reverse Transcriptase Inhibitor (NRTI)
Emtricitabine (FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus (HBV). FTC, after phosphorylated by cellular enzymes to emtricitabine 5'-triphosphate (FTC-TP), inhibits HIV and HBV reverse transcriptase (HIV-RT and HBV-RT).
References
- Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
- Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides
- Emtricitabine, a new antiretroviral agent with activity against HIV and hepatitis B virus
- Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infection
- Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV
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