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CAS RN: 212322-56-0 | Product Number: E1033
Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate
![Chemical Structure of Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate](/medias/E1033.jpg?context=bWFzdGVyfHJvb3R8NDEwNjR8aW1hZ2UvanBlZ3xhREJpTDJnMU5TODRPVEl4TmpFNE56RXdOVFU0TDBVeE1ETXpMbXB3Wnd8NmU1YTNkOWVlYmI2MjkyYjQwMGIxNjU4MmZiNmJmYjAxNDgxODZhYTRiMmVjOTc3NDQxMGQwNDZlYzczNjJlYg "Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate")
![Thumbnail of Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate](/medias/E1033.jpg?context=bWFzdGVyfHJvb3R8MTM0MDl8aW1hZ2UvanBlZ3xhR1JoTDJoaU1TODRPVE0xTURjME5EazJOVFF5TDBVeE1ETXpMbXB3Wnd8YzEzZDlmYzVlMGIyOWIxZTI1YjYyZDA4YTdmNDM1NWMyY2M3MzdmMDAzZmZmYWFhZGVhZjBiYTViYjlmMjg3Yg)
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![Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate")
Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionic Acid Ethyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
NT$714
|
5 | 0 | It can be shipped in about 2 weeks after ordering | |
| 5G |
NT$2,058
|
11 | 0 | It can be shipped in about 2 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
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* The storage conditions are subject to change without notice.
| Product Number | E1033 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__2N__4O__3 = 342.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 212322-56-0 |
| Reaxys Registry Number | 9147567 |
| PubChem Substance ID | 253661756 |
| MDL Number | MFCD09833624 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 104.0 to 108.0 °C |
Properties (reference)
| Melting Point | 106 °C |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
A Synthetic Intermediate of Dabigatran and Its Derivatives
This product has been used as a synthetic intermediate of dabigatran [D5902, D5904 (Etexilate)] and its derivatives, which are direct thrombin inhibitors.
References
- Structure-based design of novel potent nonpeptide thrombin inhibitors
- Synthesis, characterization and suppression of impurities during optimization of Dabigatran etexilate
- Design, synthesis and structural exploration of novel fluorinated dabigatran derivatives as direct thrombin inhibitors
- Gradient RP-HPLC method for the determination of potential impurities in dabigatran etexilate in bulk drug and capsule formulations
PubMed Literature
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