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CAS RN: 236395-14-5 | Product Number: E1046
Eslicarbazepine Acetate
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Purity: >98.0%(HPLC)(N)
Synonyms:
- BIA 2-093
- (S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
NT$4,788
|
1 | 0 | Contact Us | |
| 1G |
NT$15,246
|
6 | 0 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | E1046 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__7H__1__6N__2O__3 = 296.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 236395-14-5 |
| Reaxys Registry Number | 8336447 |
| PubChem Substance ID | 253662249 |
| MDL Number | MFCD06798333 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 185.0 to 189.0 °C |
| Specific rotation [a]20/D | -20.0 to -24.0 deg(C=1, Pyridine) |
Properties (reference)
| Melting Point | 187 °C |
| Specific Rotation | -22° (C=1,Pyridine) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H336 : May cause drowsiness or dizziness. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P271 : Use only outdoors or in a well-ventilated area. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Romifidine: a potent and selective α2-adrenoceptor agonist
Eslicarbazepine acetate (BIA 2-093 or ESL) is a central nervous system (CNS)-active compound with anticonvulsant activity. BIA 2-093 has voltage-gated sodium channel (VGSC) blocking property. BIA 2-093 is metabolized to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine [O0363], which is responsible for pharmacological activity. BIA 2-093 is used as a third generation antiepileptic drugs (AEDs), and is often used in combination with the other AEDs. (The product is for research purpose only.)
References
- Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives
- Metabolism of two new antiepileptic drugs and their principal metabolites S(+)- and R(-)-10,11-dihydro-10-hydroxy carbamazepine
- Enantioselective HPLC-UV method for determination of eslicarbazepine acetate (BIA 2-093) and its metabolites in human plasma
- Eslicarbazepine acetate (BIA 2-093) (a review)
- Drug interactions involving the new second- and third-generation antiepileptic drugs (a review)
PubMed Literature
Product Articles
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Specifications
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